Basic Information
ID: ALA3395429
Type: Binding
Description: Inhibition of human liver FBPase expressed in Escherichia coli BL21(DE3) Rosetta cells assessed as reduction of NADP+ to NADPH by phosphoglucose isomerase and glucose-6-phosphate dehydrogenase coupling based spectrophotometry
Format: BAO_0000219
Organism: Homo sapiens
Target: Fructose-1,6-bisphosphatase(ALA3975)
Document: ALA3392954
Inhibition of human liver FBPase expressed in Escherichia coli BL21(DE3) Rosetta cells assessed as reduction of NADP+ to NADPH by phosphoglucose isomerase and glucose-6-phosphate dehydrogenase coupling based spectrophotometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3395429
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.22 | -1.86 | -1.86 |
| 302.11 | 3.19 | 3.19 |
| 278.22 | 1.79 | 1.79 |
| 278.22 | 1.79 | 1.79 |
| 278.22 | 1.79 | 1.79 |
| 278.22 | 1.79 | 1.79 |
| 312.67 | 2.44 | 2.44 |
| 312.67 | 2.44 | 2.44 |
| 357.12 | 2.55 | 2.55 |
| 306.27 | 2.27 | 2.27 |
| 248.24 | 1.47 | 1.47 |
| 332.31 | 2.67 | 2.67 |
| 368.35 | 3.31 | 3.31 |
| 354.32 | 3.46 | 3.46 |
| 372.31 | 3.60 | 3.60 |
| 372.31 | 3.60 | 3.60 |
| 372.31 | 3.60 | 3.60 |
| 384.34 | 3.47 | 3.47 |
| 384.34 | 3.47 | 3.47 |
| 399.32 | 3.37 | 3.37 |
| 399.32 | 3.37 | 3.37 |
| 306.27 | 2.35 | 2.35 |
| 334.33 | 2.99 | 2.99 |
| 369.33 | 3.54 | 3.54 |
| 399.36 | 3.54 | 3.54 |
| 399.36 | 3.54 | 3.54 |
| 354.32 | 3.46 | 3.46 |
| 334.33 | 2.99 | 2.99 |
| 306.27 | 2.35 | 2.35 |
| 369.33 | 3.54 | 3.54 |