Basic Information
ID: ALA3396023
Type: Binding
Description: Inhibition of human recombinant CDK4/Cyclin D1 using fluoresceinyl-Ahx-Pro-Val-Lys-Arg-Arg-Leu-(3ClPhe)-Gly as substrate after 45 mins by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3396023
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 647.78 | -2.64 | -2.64 |
| 703.89 | -0.80 | -0.80 |
| 933.13 | -5.22 | -5.22 |
| 934.11 | -4.62 | -4.62 |
| 940.14 | -4.56 | -4.56 |
| 948.14 | -4.23 | -4.23 |
| 954.17 | -4.17 | -4.17 |
| 891.04 | -5.61 | -5.61 |
| 1046.33 | ||
| 1040.29 | ||
| 704.87 | -0.62 | -0.62 |
| 704.87 | -0.62 | -0.62 |
| 689.90 | 0.28 | 0.28 |
| 717.92 | -0.46 | -0.46 |
| 644.82 | 0.44 | 0.44 |
| 604.75 | -0.43 | -0.43 |
| 618.78 | -0.04 | -0.04 |
| 661.85 | -0.20 | -0.20 |
| 675.88 | 0.19 | 0.19 |
| 590.73 | -1.33 | -1.33 |
| 604.76 | -0.94 | -0.94 |
| 661.81 | -1.83 | -1.83 |
| 722.82 | -2.83 | -2.83 |
| 618.78 | -0.60 | -0.60 |
| 617.80 | -1.20 | -1.20 |
| 716.67 | 2.91 | 2.91 |
| 715.69 | 2.72 | 2.72 |
| 721.72 | 2.78 | 2.78 |
| 735.74 | 2.83 | 2.83 |
| 749.77 | 3.09 | 3.09 |
| 749.77 | 3.22 | 3.22 |
| 761.78 | 3.24 | 3.24 |