Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs

Basic Information

ID: ALA3396817

Type: Binding

Description: Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HepG2

Target: Acyl-CoA desaturase(ALA5555)

Document: ALA3393027

Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3396817

IC50

Total(29)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
424.46	2.31	2.31
424.46	2.31	2.31
492.46	3.33	3.33
430.51	1.72	1.72
439.48	2.01	2.01
414.42	1.90	1.90
414.42	1.90	1.90
430.49	2.37	2.37
444.52	2.68	2.68
413.44	1.64	1.64
427.47	1.95	1.95
427.47	1.65	1.65
427.47	1.65	1.65
333.35	1.09	1.09
474.47	3.19	3.19
442.45	2.45	2.45
464.43	2.78	2.78
454.49	2.34	2.34
370.44	1.53	1.53
406.42	1.78	1.78
426.42	2.47	2.47
474.47	3.19	3.19
438.49	2.87	2.87
393.38	1.27	1.27
393.38	1.27	1.27
393.38	1.27	1.27
383.34	0.86	0.86
396.39	0.61	0.61
316.30	0.30	0.30