Basic Information
ID: ALA3396841
Type: ADME
Description: Therapeutic index, ratio of toxicity in female Sprague-Dawley rat at 100 mg/kg, po once daily for 10 consecutive days to antiobesity activity in Lewis rat DI model assessed as reduction in plasma C16:1/C16:0 TG desaturation index at 5 mg/kg, po after 4 hrs
Format: BAO_0000218
Organism: Rattus norvegicus
Tissue: Plasma
Target: ADMET(ALA612558)
Document: ALA3393027
Therapeutic index, ratio of toxicity in female Sprague-Dawley rat at 100 mg/kg, po once daily for 10 consecutive days to antiobesity activity in Lewis rat DI model assessed as reduction in plasma C16:1/C16:0 TG desaturation index at 5 mg/kg, po after 4 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3396841
TI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.38 | 1.27 | 1.27 |