Assay Report Card

Basic Information

ID: ALA3396841

Type: ADME

Description: Therapeutic index, ratio of toxicity in female Sprague-Dawley rat at 100 mg/kg, po once daily for 10 consecutive days to antiobesity activity in Lewis rat DI model assessed as reduction in plasma C16:1/C16:0 TG desaturation index at 5 mg/kg, po after 4 hrs

Organism: Rattus norvegicus

Tissue: Plasma

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
393.381.271.27