ID: ALA3398675
Type: Binding
Description: Inhibition of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as inhibition of amyloid beta 42 formation after 24 hrs by ELISA
Organism: Homo sapiens
Cell type: CHO
Bioactivity
Activity Types for Assay ALA3398675
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
466.60 | 5.46 | 5.46 |
478.70 | 6.91 | 6.91 |
552.51 | 8.54 | 8.54 |
454.49 | 7.61 | 7.61 |
470.49 | 7.73 | 7.73 |
484.51 | 7.52 | 7.52 |
510.55 | 8.03 | 8.03 |
540.62 | 8.86 | 8.86 |
560.61 | 9.19 | 9.19 |
590.64 | 9.10 | 9.10 |
502.50 | 7.66 | 7.66 |
553.40 | 8.83 | 8.83 |
620.51 | 9.56 | 9.56 |
485.50 | 6.92 | 6.92 |
540.60 | 8.74 | 8.74 |
635.63 | 9.66 | 9.66 |
633.59 | 9.10 | 9.10 |
581.66 | 8.95 | 8.95 |
577.60 | 8.71 | 8.71 |
613.67 | 7.23 | 7.23 |
394.39 | 5.65 | 5.65 |
574.64 | 9.15 | 9.15 |
558.56 | 8.69 | 8.69 |
566.54 | 8.58 | 8.58 |