Basic Information
ID: ALA3398679
Type: Binding
Description: Inhibition of 5-LO in human human PMNL assessed as reduction in 5-LO product formation pre-incubated for 15 mins before addition of arachidonic acid substrate by HPLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3398679
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.60 | 5.46 | 5.46 |
| 478.70 | 6.91 | 6.91 |
| 552.51 | 8.54 | 8.54 |
| 454.49 | 7.61 | 7.61 |
| 470.49 | 7.73 | 7.73 |
| 484.51 | 7.52 | 7.52 |
| 510.55 | 8.03 | 8.03 |
| 540.62 | 8.86 | 8.86 |
| 560.61 | 9.19 | 9.19 |
| 590.64 | 9.10 | 9.10 |
| 502.50 | 7.66 | 7.66 |
| 553.40 | 8.83 | 8.83 |
| 620.51 | 9.56 | 9.56 |
| 485.50 | 6.92 | 6.92 |
| 540.60 | 8.74 | 8.74 |
| 635.63 | 9.66 | 9.66 |
| 633.59 | 9.10 | 9.10 |
| 581.66 | 8.95 | 8.95 |
| 577.60 | 8.71 | 8.71 |
| 613.67 | 7.23 | 7.23 |
| 394.39 | 5.65 | 5.65 |
| 574.64 | 9.15 | 9.15 |
| 558.56 | 8.69 | 8.69 |
| 566.54 | 8.58 | 8.58 |