Basic Information
ID: ALA3398845
Type: ADME
Description: Inhibition of human MDR1 expressed in MDCK2 cells assessed as increase of rhodamine 123 uptake at 30 uM up to 240 mins relative to 5 uM tariquidar
Organism: Homo sapiens
Cell type: MDCK-II
Activity Charts
Bioactivity
Activity Types for Assay ALA3398845
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.97 | 3.80 | 3.80 |
| 501.03 | 4.95 | 4.95 |
| 463.97 | 4.74 | 4.74 |
| 462.98 | 4.69 | 4.69 |
| 428.54 | 4.04 | 4.04 |
| 477.01 | 4.71 | 4.71 |
| 477.01 | 4.56 | 4.56 |
| 442.56 | 3.90 | 3.90 |
| 491.04 | 4.60 | 4.60 |
| 475.98 | 4.18 | 4.18 |
| 461.99 | 4.54 | 4.54 |