Basic Information
ID: ALA3399054
Type: Binding
Description: Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cells assessed as inhibition of methylation of nucleosomes at H3K27 at 20 uM by scintillation counting in presence of [3H]SAM
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA3399054
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.41 | -0.89 | -0.89 |
| 381.39 | -2.24 | -2.24 |
| 398.45 | -0.98 | -0.98 |
| 426.50 | -0.20 | -0.20 |
| 474.54 | 0.59 | 0.59 |
| 369.40 | -0.37 | -0.37 |
| 411.49 | -1.43 | -1.43 |
| 437.53 | -0.90 | -0.90 |
| 485.57 | 0.02 | 0.02 |
| 463.52 | -1.15 | -1.15 |
| 491.58 | -1.43 | -1.43 |