Basic Information
ID: ALA3399055
Type: Binding
Description: Inhibition of N-terminally FLAG-tagged EZH2 Y641N mutant in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cells assessed as inhibition of methylation of nucleosomes at H3K27 by scintillation counting in presence of [3H]SAM
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA3399055
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.42 | -1.44 | -1.44 |
| 491.58 | -0.99 | -0.99 |
| 553.65 | 0.04 | 0.04 |
| 553.65 | 0.29 | 0.29 |
| 557.61 | 0.12 | 0.12 |
| 532.63 | -1.56 | -1.56 |
| 608.73 | 0.01 | 0.01 |
| 531.64 | -0.20 | -0.20 |
| 517.62 | -0.21 | -0.21 |
| 519.63 | -0.18 | -0.18 |
| 507.58 | -1.34 | -1.34 |
| 539.62 | 0.18 | 0.18 |