Basic Information
ID: ALA3399217
Type: Functional
Description: Antagonist activity against human OX1 receptor expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated for 30 mins by Fluo-4 AM dye based fluorescence assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3399217
Kb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.46 | 3.14 | 3.14 |
| 469.47 | 4.02 | 4.02 |
| 469.47 | 4.02 | 4.02 |
| 469.47 | 4.02 | 4.02 |
| 415.50 | 3.30 | 3.30 |
| 418.48 | 3.74 | 3.74 |
| 421.44 | 2.86 | 2.86 |
| 419.46 | 3.14 | 3.14 |
| 420.45 | 3.47 | 3.47 |
| 420.45 | 3.47 | 3.47 |
| 391.41 | 2.40 | 2.40 |
| 405.44 | 2.75 | 2.75 |
| 433.49 | 3.52 | 3.52 |
| 423.43 | 2.97 | 2.97 |
| 439.88 | 3.48 | 3.48 |
| 435.46 | 2.84 | 2.84 |
| 430.49 | 4.01 | 4.01 |
| 405.44 | 2.83 | 2.83 |