Basic Information
ID: ALA3399535
Type: Binding
Description: Inhibition of T3SS-mediated translocation in Pseudomonas aerguinosa PA99U co-expressing PcrV and PopB/PopD assessed as inhibition of ExoU-mediated lysis of co-incubated CHO cells by LDH release assay
Organism: Pseudomonas aeruginosa
Strain: PA99U
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3399535
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.22 | 3.81 | 3.81 |
| 354.19 | 3.42 | 3.42 |
| 382.24 | 4.20 | 4.20 |
| 382.24 | 4.20 | 4.20 |
| 396.27 | 4.59 | 4.59 |
| 396.27 | 4.44 | 4.44 |
| 368.22 | 3.81 | 3.81 |
| 368.22 | 3.81 | 3.81 |
| 333.77 | 3.15 | 3.15 |
| 333.77 | 3.15 | 3.15 |
| 351.76 | 3.29 | 3.29 |
| 351.76 | 3.29 | 3.29 |
| 335.31 | 2.78 | 2.78 |
| 347.80 | 3.46 | 3.46 |
| 358.78 | 3.02 | 3.02 |
| 363.80 | 3.16 | 3.16 |
| 369.20 | 3.20 | 3.20 |
| 342.20 | 4.22 | 4.22 |
| 384.28 | 4.52 | 4.52 |
| 358.26 | 4.93 | 4.93 |
| 416.28 | 3.20 | 3.20 |
| 390.26 | 3.61 | 3.61 |
| 367.23 | 3.84 | 3.84 |
| 341.21 | 4.25 | 4.25 |
| 366.24 | 4.22 | 4.22 |
| 340.23 | 4.63 | 4.63 |
| 356.22 | 4.78 | 4.78 |
| 356.22 | 4.78 | 4.78 |
| 356.22 | 4.78 | 4.78 |
| 370.25 | 4.95 | 4.95 |
| 368.24 | 4.71 | 4.71 |
| 370.25 | 5.17 | 5.17 |
| 384.28 | 5.56 | 5.56 |
| 384.28 | 5.41 | 5.41 |
| 382.26 | 5.17 | 5.17 |
| 398.31 | 5.95 | 5.95 |
| 396.29 | 5.56 | 5.56 |
| 372.22 | 3.75 | 3.75 |
| 367.21 | 4.28 | 4.28 |
| 400.23 | 3.93 | 3.93 |
| 386.21 | 3.84 | 3.84 |
| 328.17 | 4.54 | 4.54 |
| 356.22 | 4.26 | 4.26 |
| 370.25 | 4.65 | 4.65 |
| 356.22 | 4.56 | 4.56 |
| 343.18 | 4.64 | 4.64 |
| 357.21 | 4.69 | 4.69 |
| 343.19 | 4.04 | 4.04 |
| 357.21 | 3.72 | 3.72 |
| 358.20 | 4.15 | 4.15 |
| 341.21 | 5.10 | 5.10 |
| 324.21 | 4.08 | 4.08 |
| 342.20 | 4.22 | 4.22 |
| 342.20 | 4.22 | 4.22 |
| 358.65 | 4.73 | 4.73 |
| 358.65 | 4.73 | 4.73 |
| 358.65 | 4.73 | 4.73 |
| 338.23 | 4.39 | 4.39 |
| 338.23 | 4.39 | 4.39 |
| 338.23 | 4.39 | 4.39 |
| 354.23 | 4.09 | 4.09 |
| 354.23 | 4.09 | 4.09 |
| 354.23 | 4.09 | 4.09 |
| 384.26 | 4.09 | 4.09 |
| 384.26 | 4.09 | 4.09 |
| 380.30 | 5.29 | 5.29 |
| 364.23 | 4.82 | 4.82 |
| 364.23 | 3.95 | 3.95 |
| 363.24 | 4.56 | 4.56 |
| 363.24 | 4.56 | 4.56 |
| 363.24 | 4.56 | 4.56 |
| 363.24 | 4.56 | 4.56 |
| 377.27 | 4.57 | 4.57 |
| 364.23 | 3.95 | 3.95 |
| 343.19 | 3.61 | 3.61 |
| 343.19 | 3.61 | 3.61 |
| 395.31 | 5.08 | 5.08 |
| 378.26 | 4.34 | 4.34 |
| 387.24 | 3.53 | 3.53 |