Basic Information
ID: ALA3399803
Type: Binding
Description: Inhibition of CYP11B1 in human V79MZ cells using [3H]-11-deoxycorticosterone as substrate incubated for 1 hr prior to substrate addition measured after 25 mins by HPLC analysis
Organism: Homo sapiens
Cell type: V79MZ
Activity Charts
Bioactivity
Activity Types for Assay ALA3399803
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.28 | 2.68 | 2.68 |
| 224.26 | 2.63 | 2.63 |
| 242.30 | 2.79 | 2.79 |
| 227.24 | 2.43 | 2.43 |
| 226.24 | 2.08 | 2.08 |
| 212.21 | 2.18 | 2.18 |
| 240.26 | 2.10 | 2.10 |
| 276.30 | 3.23 | 3.23 |
| 225.25 | 2.11 | 2.11 |
| 239.28 | 2.14 | 2.14 |
| 275.31 | 3.27 | 3.27 |
| 226.24 | 2.81 | 2.81 |
| 276.30 | 3.96 | 3.96 |
| 225.25 | 2.38 | 2.38 |
| 275.31 | 3.54 | 3.54 |
| 262.29 | 1.84 | 1.84 |
| 276.32 | 1.86 | 1.86 |
| 312.35 | 2.99 | 2.99 |
| 274.30 | 1.69 | 1.69 |