Basic Information
ID: ALA3404113
Type: Binding
Description: Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H]choline by [3H]choline uptake assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3404113
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.53 | 3.99 | 3.99 |
| 386.50 | 2.61 | 2.61 |
| 428.58 | 3.71 | 3.71 |
| 400.52 | 3.09 | 3.09 |
| 389.54 | 2.77 | 2.77 |
| 290.32 | 2.44 | 2.44 |
| 402.56 | 4.25 | 4.25 |
| 384.48 | 2.67 | 2.67 |
| 400.52 | 2.92 | 2.92 |
| 358.44 | 4.06 | 4.06 |
| 403.55 | 3.64 | 3.64 |
| 403.55 | 3.64 | 3.64 |
| 411.55 | 3.70 | 3.70 |
| 372.47 | 4.45 | 4.45 |
| 387.48 | 3.21 | 3.21 |
| 375.47 | 3.07 | 3.07 |
| 387.48 | 3.21 | 3.21 |
| 401.51 | 3.60 | 3.60 |
| 403.48 | 2.45 | 2.45 |
| 373.45 | 2.87 | 2.87 |
| 387.48 | 3.21 | 3.21 |
| 346.43 | 3.77 | 3.77 |