Basic Information
ID: ALA3404606
Type: Binding
Description: Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3404606
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.56 | 3.63 | 3.63 |
| 223.30 | 1.91 | 1.91 |
| 237.33 | 2.30 | 2.30 |
| 237.33 | 2.30 | 2.30 |
| 236.34 | 2.68 | 2.68 |
| 251.35 | 2.69 | 2.69 |
| 235.31 | 2.05 | 2.05 |
| 249.34 | 2.44 | 2.44 |
| 279.37 | 2.07 | 2.07 |
| 293.39 | 2.19 | 2.19 |
| 335.43 | 2.62 | 2.62 |
| 321.40 | 2.53 | 2.53 |
| 314.41 | 3.36 | 3.36 |
| 303.39 | 3.56 | 3.56 |
| 348.50 | 4.04 | 4.04 |
| 344.44 | 3.37 | 3.37 |
| 315.40 | 2.76 | 2.76 |
| 320.46 | 2.77 | 2.77 |
| 362.54 | 3.89 | 3.89 |
| 397.55 | 4.08 | 4.08 |
| 362.50 | 3.02 | 3.02 |
| 362.50 | 3.02 | 3.02 |
| 348.47 | 2.63 | 2.63 |
| 376.53 | 3.27 | 3.27 |
| 390.55 | 3.66 | 3.66 |
| 410.54 | 3.93 | 3.93 |
| 411.53 | 3.32 | 3.32 |
| 425.56 | 3.63 | 3.63 |