Basic Information
ID: ALA3404758
Type: Functional
Description: Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3404758
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.59 | 4.86 | 4.86 |
| 519.59 | 5.18 | 5.18 |
| 515.61 | 5.78 | 5.78 |
| 517.62 | 5.39 | 5.39 |
| 556.62 | 4.66 | 4.66 |
| 609.70 | 3.85 | 3.85 |
| 671.77 | 5.28 | 5.28 |
| 488.58 | 5.40 | 5.40 |
| 518.61 | 4.77 | 4.77 |
| 541.65 | 5.19 | 5.19 |
| 539.64 | 5.58 | 5.58 |
| 531.61 | 5.61 | 5.61 |
| 541.60 | 5.97 | 5.97 |
| 542.59 | 5.98 | 5.98 |
| 527.62 | 6.54 | 6.54 |