Basic Information
ID: ALA3405148
Type: ADME
Description: Drug metabolism in Sprague-Dawley rat liver S9 fraction assessed as 2-(3-aminopiperidin-1-yl)-3-(2-chlorobenzyl)-5-methyl-4-oxo-4,5-dihydro-3H-imidazo[4,5-c]quinoline-8-carboxylic acid formation at 1 uM after 30 mins by HPLC/MS/MS analysis relative to control
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Liver S9 fraction
Activity Charts
Bioactivity
Activity Types for Assay ALA3405148
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.43 | 3.30 | 3.30 |
| 616.55 | 4.22 | 4.22 |
| 573.53 | 3.24 | 3.24 |
| 587.55 | 3.63 | 3.63 |
| 615.56 | 3.01 | 3.01 |
| 629.59 | 3.40 | 3.40 |
| 643.62 | 3.78 | 3.78 |
| 614.49 | 3.73 | 3.73 |
| 632.48 | 3.87 | 3.87 |