Basic Information
ID: ALA3405420
Type: Binding
Description: Antagonist activity at Sprague-Dawley rat ETA receptor assessed as inhibition of ET1-induced contraction of thoracic aortic ring at 10 uM after 30 mins
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA3405420
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 610.71 | 0.83 | 0.83 |
| 404.46 | 5.45 | 5.45 |
| 438.91 | 6.11 | 6.11 |
| 434.49 | 5.46 | 5.46 |
| 434.49 | 5.46 | 5.46 |
| 448.47 | 5.18 | 5.18 |
| 462.53 | 5.46 | 5.46 |
| 406.43 | 4.95 | 4.95 |
| 440.88 | 5.60 | 5.60 |
| 436.46 | 4.96 | 4.96 |
| 436.46 | 4.96 | 4.96 |
| 387.44 | 5.12 | 5.12 |
| 431.44 | 4.85 | 4.85 |
| 429.43 | 4.66 | 4.66 |
| 445.50 | 5.13 | 5.13 |
| 387.44 | 5.39 | 5.39 |
| 431.44 | 5.12 | 5.12 |