Basic Information
ID: ALA3405540
Type: Binding
Description: Inhibition of mouse mGAT1 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintillation counting analysis
Format: BAO_0000219
Organism: Mus musculus
Cell type: HEK293
Target: GABA transporter 1(ALA5445)
Document: ALA3399947
Inhibition of mouse mGAT1 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintillation counting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3405540
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 263.38 | 3.83 | 3.83 |
| 505.61 | 4.82 | 4.82 |
| 375.56 | 5.04 | 5.04 |
| 414.55 | 5.18 | 5.18 |
| 403.61 | 5.82 | 5.82 |
| 401.60 | 5.74 | 5.74 |
| 403.61 | 5.82 | 5.82 |
| 403.61 | 5.82 | 5.82 |
| 380.49 | 4.03 | 4.03 |
| 389.54 | 5.18 | 5.18 |
| 389.54 | 5.18 | 5.18 |
| 503.48 | 6.41 | 6.41 |
| 403.61 | 5.82 | 5.82 |
| 380.49 | 4.03 | 4.03 |
| 380.49 | 4.03 | 4.03 |
| 389.54 | 5.18 | 5.18 |
| 389.54 | 5.18 | 5.18 |
| 503.48 | 6.41 | 6.41 |
| 503.48 | 6.41 | 6.41 |
| 378.47 | 3.95 | 3.95 |
| 387.52 | 5.10 | 5.10 |
| 501.47 | 6.33 | 6.33 |
| 389.63 | 5.73 | 5.73 |
| 389.63 | 5.73 | 5.73 |
| 366.51 | 3.94 | 3.94 |
| 366.51 | 3.94 | 3.94 |
| 375.56 | 5.09 | 5.09 |
| 375.56 | 5.09 | 5.09 |
| 489.50 | 6.31 | 6.31 |
| 489.50 | 6.31 | 6.31 |
| 431.67 | 6.30 | 6.30 |
| 431.67 | 6.30 | 6.30 |
| 408.54 | 4.51 | 4.51 |
| 417.59 | 5.66 | 5.66 |
| 417.59 | 5.66 | 5.66 |
| 531.54 | 6.88 | 6.88 |
| 531.54 | 6.88 | 6.88 |
| 277.46 | 4.47 | 4.47 |
| 254.33 | 2.68 | 2.68 |
| 377.33 | 5.05 | 5.05 |
| 376.55 | 3.61 | 3.61 |
| 353.42 | 1.81 | 1.81 |
| 476.42 | 4.19 | 4.19 |
| 158.20 | -0.64 | -0.64 |
| 376.55 | 3.61 | 3.61 |
| 353.42 | 1.81 | 1.81 |
| 158.20 | -0.64 | -0.64 |
| 335.49 | 4.31 | 4.31 |
| 312.37 | 2.52 | 2.52 |
| 321.42 | 3.67 | 3.67 |
| 349.52 | 4.65 | 4.65 |
| 326.40 | 2.86 | 2.86 |
| 335.45 | 4.01 | 4.01 |
| 376.39 | 2.96 | 2.96 |
| 385.44 | 4.11 | 4.11 |
| 376.48 | 2.67 | 2.67 |
| 416.57 | 4.10 | 4.10 |
| 516.44 | 4.69 | 4.69 |
| 390.57 | 3.85 | 3.85 |
| 418.63 | 4.59 | 4.59 |
| 446.68 | 5.37 | 5.37 |
| 446.68 | 5.37 | 5.37 |
| 430.64 | 4.75 | 4.75 |
| 480.70 | 5.77 | 5.77 |
| 434.63 | 3.56 | 3.56 |
| 432.62 | 3.46 | 3.46 |
| 367.45 | 2.06 | 2.06 |
| 395.50 | 2.79 | 2.79 |
| 423.56 | 3.57 | 3.57 |
| 613.85 | 7.04 | 7.04 |
| 411.50 | 1.77 | 1.77 |