Basic Information
ID: ALA3405554
Type: Binding
Description: Inhibition of human NPC1L1 transfected in MDCK2 cells assessed as [3H]cholesterol uptake after 1 hr by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: MDCK-II
Activity Charts
Bioactivity
Activity Types for Assay ALA3405554
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.43 | 3.82 | 3.82 |
| 420.42 | 3.96 | 3.96 |
| 390.41 | 3.35 | 3.35 |
| 408.40 | 3.49 | 3.49 |
| 376.39 | 3.42 | 3.42 |
| 394.38 | 3.56 | 3.56 |