Assay Report Card

Basic Information

ID: ALA3405605

Type: Functional

Description: Antihypertensive activity in Sprague-Dawley rat PAH model assessed as reduction in hypoxia-induced elevated right ventricular systolic pressure at 40 mg/kg, po administered for 28 days measured on day 29 relative to untreated control

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Heart right ventricle

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
448.475.185.18