Basic Information
ID: ALA3406495
Type: Binding
Description: Inhibition of HIF1 in human HT1080 cells transfected with 5xHRE/pGL3/VEGF/E1b reporter plasmid pre-incubated for 1 hr followed by incubation under hypoxia conditions for 24 hrs by HRE-driven luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HT-1080
Activity Charts
Bioactivity
Activity Types for Assay ALA3406495
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 304.35 | 3.84 | 3.84 |
| 356.39 | 1.71 | 1.71 |
| 372.45 | 2.18 | 2.18 |
| 366.43 | 2.12 | 2.12 |
| 370.41 | 1.97 | 1.97 |
| 384.44 | 2.31 | 2.31 |
| 328.33 | 1.22 | 1.22 |
| 356.39 | 1.71 | 1.71 |
| 354.37 | 1.33 | 1.33 |
| 328.33 | 1.09 | 1.09 |
| 357.37 | 2.04 | 2.04 |
| 390.83 | 2.36 | 2.36 |
| 435.28 | 2.47 | 2.47 |