Basic Information
ID: ALA3406503
Type: Binding
Description: Inhibition of multidrug resistance efflux pump in wild-type Escherichia coli AB1157 assessed as concentration required to reduce piperacillin MIC by 4-fold by checkerboard assay
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA3406503
INH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.54 | 3.62 | 3.62 |
| 395.53 | 3.93 | 3.93 |
| 358.47 | 2.65 | 2.65 |
| 367.52 | 4.21 | 4.21 |
| 395.57 | 4.99 | 4.99 |
| 393.56 | 4.74 | 4.74 |
| 422.60 | 3.89 | 3.89 |
| 466.65 | 3.91 | 3.91 |
| 425.62 | 4.69 | 4.69 |
| 453.68 | 5.47 | 5.47 |
| 422.60 | 3.94 | 3.94 |
| 436.63 | 4.28 | 4.28 |
| 423.58 | 4.37 | 4.37 |
| 401.50 | 1.49 | 1.49 |
| 410.54 | 3.37 | 3.37 |
| 410.54 | 3.37 | 3.37 |
| 439.58 | 3.98 | 3.98 |
| 439.58 | 3.98 | 3.98 |
| 439.58 | 3.98 | 3.98 |
| 467.59 | 3.90 | 3.90 |
| 427.55 | 4.12 | 4.12 |
| 427.55 | 4.12 | 4.12 |
| 427.55 | 4.12 | 4.12 |
| 444.00 | 4.63 | 4.63 |
| 448.59 | 4.46 | 4.46 |
| 449.58 | 4.72 | 4.72 |
| 434.57 | 3.85 | 3.85 |
| 477.59 | 3.16 | 3.16 |
| 489.62 | 3.22 | 3.22 |
| 469.61 | 3.99 | 3.99 |
| 467.64 | 3.30 | 3.30 |
| 467.64 | 3.30 | 3.30 |
| 467.64 | 3.30 | 3.30 |
| 462.62 | 2.43 | 2.43 |
| 496.68 | 3.92 | 3.92 |
| 496.68 | 3.92 | 3.92 |
| 526.70 | 3.92 | 3.92 |
| 484.64 | 4.05 | 4.05 |
| 484.64 | 4.05 | 4.05 |
| 545.55 | 4.67 | 4.67 |
| 482.65 | 3.74 | 3.74 |
| 438.60 | 4.15 | 4.15 |
| 467.64 | 4.76 | 4.76 |
| 455.60 | 4.89 | 4.89 |
| 552.74 | 6.10 | 6.10 |
| 452.62 | 4.34 | 4.34 |
| 494.66 | 4.71 | 4.71 |
| 548.63 | 5.25 | 5.25 |
| 530.72 | 4.12 | 4.12 |
| 506.67 | 4.88 | 4.88 |
| 536.74 | 5.74 | 5.74 |
| 494.67 | 4.06 | 4.06 |
| 409.56 | 3.98 | 3.98 |
| 442.59 | 3.41 | 3.41 |
| 427.57 | 3.20 | 3.20 |
| 425.55 | 2.99 | 2.99 |
| 441.55 | 2.66 | 2.66 |
| 423.58 | 4.37 | 4.37 |
| 425.55 | 3.47 | 3.47 |
| 381.50 | 3.20 | 3.20 |
| 382.49 | 2.59 | 2.59 |