Basic Information
ID: ALA3411111
Type: Binding
Description: Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as substrate preincubated for 15 mins followed by substrate addition measured for 12 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3411111
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 276.61 | 3.04 | 3.04 |
| 232.15 | 2.93 | 2.93 |
| 265.71 | 3.30 | 3.30 |
| 215.70 | 2.42 | 2.42 |
| 227.74 | 2.29 | 2.29 |
| 265.71 | 3.30 | 3.30 |
| 232.15 | 2.93 | 2.93 |
| 215.70 | 2.42 | 2.42 |
| 276.61 | 3.04 | 3.04 |
| 232.15 | 2.93 | 2.93 |
| 276.61 | 3.04 | 3.04 |
| 352.70 | 4.27 | 4.27 |
| 352.70 | 4.27 | 4.27 |
| 308.25 | 4.16 | 4.16 |
| 291.80 | 3.64 | 3.64 |
| 374.71 | 4.94 | 4.94 |
| 330.26 | 4.83 | 4.83 |
| 374.71 | 4.94 | 4.94 |
| 313.80 | 4.32 | 4.32 |
| 330.26 | 4.83 | 4.83 |
| 338.68 | 3.88 | 3.88 |
| 294.23 | 3.77 | 3.77 |
| 277.77 | 3.25 | 3.25 |
| 324.65 | 3.79 | 3.79 |
| 280.20 | 3.68 | 3.68 |
| 281.70 | 3.18 | 3.18 |
| 294.60 | 3.18 | 3.18 |
| 215.70 | 2.42 | 2.42 |