Basic Information
ID: ALA3411306
Type: ADME
Description: Inhibition of CYP3A4 (unknown origin) assessed as reduction in midazolam hydroxylation to 1'-Hydroxymidazolam at 10 uM
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3411306
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.50 | 4.72 | 4.72 |
| 442.52 | 5.02 | 5.02 |
| 446.49 | 4.85 | 4.85 |
| 387.44 | 3.96 | 3.96 |
| 405.43 | 4.10 | 4.10 |
| 421.89 | 4.62 | 4.62 |
| 421.89 | 4.62 | 4.62 |
| 421.89 | 4.62 | 4.62 |
| 401.47 | 4.27 | 4.27 |
| 417.47 | 3.97 | 3.97 |
| 417.47 | 3.97 | 3.97 |
| 453.91 | 5.07 | 5.07 |
| 452.92 | 5.03 | 5.03 |
| 480.98 | 5.63 | 5.63 |
| 467.93 | 5.72 | 5.72 |