Basic Information
ID: ALA3411805
Type: Binding
Description: Displacement of [3H]-SAM from recombinant His6-tagged PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) at 10 uM incubated for 5 mins prior to H4(1 to 20)-BTN peptide addition measured after 8 mins by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3411805
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 492.45 | 5.70 | 5.70 |
| 512.48 | 6.34 | 6.34 |
| 568.59 | 7.90 | 7.90 |
| 645.73 | 9.57 | 9.57 |
| 612.60 | 8.65 | 8.65 |
| 668.71 | 10.21 | 10.21 |
| 315.20 | 3.10 | 3.10 |
| 343.25 | 3.88 | 3.88 |
| 806.33 | 13.00 | 13.00 |
| 358.32 | 4.72 | 4.72 |
| 498.45 | 5.95 | 5.95 |
| 526.51 | 6.73 | 6.73 |
| 541.58 | 7.56 | 7.56 |
| 523.58 | 6.03 | 6.03 |
| 602.64 | 4.93 | 4.93 |
| 605.40 | 7.49 | 7.49 |
| 464.63 | 4.87 | 4.87 |
| 581.37 | 7.65 | 7.65 |
| 637.48 | 9.21 | 9.21 |
| 714.62 | 10.87 | 10.87 |
| 670.27 | 7.87 | 7.87 |
| 726.38 | 9.43 | 9.43 |
| 803.52 | 11.09 | 11.09 |
| 745.85 | 11.87 | 11.87 |
| 548.56 | 7.26 | 7.26 |
| 625.70 | 8.92 | 8.92 |
| 650.24 | 7.22 | 7.22 |
| 706.35 | 8.78 | 8.78 |
| 706.35 | 8.78 | 8.78 |
| 592.57 | 8.00 | 8.00 |
| 648.68 | 9.56 | 9.56 |
| 772.82 | 11.23 | 11.23 |
| 562.59 | 7.65 | 7.65 |
| 650.70 | 9.34 | 9.34 |
| 606.60 | 8.39 | 8.39 |
| 831.31 | 10.70 | 10.70 |
| 638.64 | 9.20 | 9.20 |
| 673.08 | 9.77 | 9.77 |
| 818.89 | 12.43 | 12.43 |