Basic Information
ID: ALA3411809
Type: Binding
Description: Displacement of [3H]-SAM from recombinant His6-tagged PRMT5 (unknown origin) expressed in Escherichia coli BL21(DE3) incubated for 5 mins prior to H4(1 to 20)-BTN peptide addition measured after 8 mins by scintillation proximity assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Protein arginine N-methyltransferase 5(ALA1795116)
Document: ALA3407369
Displacement of [3H]-SAM from recombinant His6-tagged PRMT5 (unknown origin) expressed in Escherichia coli BL21(DE3) incubated for 5 mins prior to H4(1 to 20)-BTN peptide addition measured after 8 mins by scintillation proximity assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3411809
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 745.85 | 11.87 | 11.87 |
| 706.35 | 8.78 | 8.78 |
| 772.82 | 11.23 | 11.23 |
| 831.31 | 10.70 | 10.70 |