Basic Information
ID: ALA3412860
Type: Binding
Description: Inhibition of GARFTase/AICARFTase in human KB cells expressing RFC/FRalpha/PCFT assessed as cell growth inhibition at 1 to 1000 nM after 96 hrs by CellTiter-Blue assay in presence of 10 uM thymidine
Organism: Homo sapiens
Cell type: KB
Activity Charts
Bioactivity
Activity Types for Assay ALA3412860
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.50 | 1.51 | 1.51 |
| 447.47 | 1.12 | 1.12 |
| 461.50 | 1.51 | 1.51 |
| 475.53 | 1.90 | 1.90 |