Assay Report Card

Basic Information

ID: ALA3412862

Type: Binding

Description: Inhibition of GARFTase in human KB cells expressing RFC/FRalpha/PCFT assessed as incorporation of [U-14C]-glycine into [14C]-formyl glycinamide ribonucleotide incubated for 1 hr followed by [U-14C]-glycine addition measured after 16 hrs

Organism: Homo sapiens

Cell type: KB

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
427.420.670.67
461.501.511.51
461.501.511.51