Basic Information
ID: ALA3413143
Type: Binding
Description: Inhibition of human KMO transfected in CHO cells assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysis
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3413143
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 234.64 | 2.50 | 2.50 |
| 269.09 | 3.15 | 3.15 |
| 200.20 | 1.84 | 1.84 |
| 201.19 | 1.24 | 1.24 |
| 206.24 | 2.22 | 2.22 |
| 209.21 | 0.01 | 0.01 |
| 285.09 | 3.27 | 3.27 |
| 284.10 | 3.23 | 3.23 |
| 276.30 | 3.51 | 3.51 |
| 268.10 | 3.75 | 3.75 |
| 268.10 | 3.75 | 3.75 |
| 283.11 | 3.46 | 3.46 |
| 287.08 | 3.29 | 3.29 |
| 285.09 | 2.85 | 2.85 |
| 299.11 | 3.16 | 3.16 |
| 283.11 | 3.46 | 3.46 |
| 284.10 | 2.73 | 2.73 |
| 313.14 | 3.30 | 3.30 |
| 293.12 | 2.63 | 2.63 |
| 309.11 | 2.79 | 2.79 |
| 408.27 | 3.57 | 3.57 |
| 380.26 | 4.25 | 4.25 |
| 307.14 | 2.64 | 2.64 |
| 307.14 | 2.64 | 2.64 |
| 250.09 | 3.32 | 3.32 |
| 240.09 | 3.03 | 3.03 |
| 291.14 | 3.64 | 3.64 |
| 291.14 | 3.64 | 3.64 |
| 293.11 | 3.50 | 3.50 |
| 307.14 | 2.93 | 2.93 |
| 321.17 | 2.94 | 2.94 |
| 318.19 | 2.82 | 2.82 |
| 344.20 | 4.70 | 4.70 |
| 282.13 | 3.41 | 3.41 |
| 234.64 | 2.50 | 2.50 |
| 269.09 | 3.15 | 3.15 |
| 218.19 | 1.98 | 1.98 |
| 252.63 | 2.63 | 2.63 |
| 252.63 | 2.63 | 2.63 |
| 252.63 | 2.63 | 2.63 |
| 236.18 | 2.12 | 2.12 |
| 236.18 | 2.12 | 2.12 |
| 252.63 | 2.63 | 2.63 |
| 302.64 | 3.51 | 3.51 |
| 268.19 | 2.86 | 2.86 |
| 268.19 | 2.86 | 2.86 |
| 214.22 | 2.15 | 2.15 |
| 286.18 | 3.00 | 3.00 |
| 248.67 | 2.80 | 2.80 |
| 232.21 | 2.29 | 2.29 |
| 264.67 | 2.50 | 2.50 |
| 363.80 | 2.21 | 2.21 |
| 363.80 | 2.21 | 2.21 |
| 303.75 | 3.10 | 3.10 |
| 318.64 | 3.39 | 3.39 |
| 264.67 | 2.50 | 2.50 |
| 292.72 | 3.28 | 3.28 |
| 290.71 | 3.04 | 3.04 |
| 304.73 | 3.28 | 3.28 |
| 240.22 | 2.59 | 2.59 |
| 304.73 | 3.43 | 3.43 |
| 306.71 | 2.27 | 2.27 |
| 318.76 | 3.82 | 3.82 |
| 332.79 | 4.21 | 4.21 |