Effective efflux ratio of apparent permeability in MDCK cells overexpressing PGP at 10 uM to wild-type MDCK cells at 10 uM

Basic Information

ID: ALA3413301

Type: ADME

Description: Effective efflux ratio of apparent permeability in MDCK cells overexpressing PGP at 10 uM to wild-type MDCK cells at 10 uM

Format: BAO_0000219

Organism: Canis lupus familiaris

Cell type: MDCK

Target:  MDCK(ALA614068)

Document:  ALA3407478

Effective efflux ratio of apparent permeability in MDCK cells overexpressing PGP at 10 uM to wild-type MDCK cells at 10 uM: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
318.643.393.39
264.672.502.50
292.723.283.28
290.713.043.04
304.733.283.28
240.222.592.59
304.733.433.43
306.712.272.27
318.763.823.82
332.794.214.21