Assay Report Card

Basic Information

ID: ALA3413641

Type: Binding

Description: Inhibition of human recombinant myostatin pre-incubated with 30 uM compound for 1 hr before addition to human HepG2 cells assessed as reduction in myostatin-mediated downstream transcriptional response by myostatin-responsive (CAGA)12-luciferase reporter gene assay

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
2574.04
2956.55
2885.47
1394.82
2699.25
2414.93
2199.73
1880.36
2843.39
2687.20