Basic Information
ID: ALA3414385
Type: ADME
Description: Inhibition of CYP3A4 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysis
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3414385
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.43 | -0.91 | -0.91 |
| 408.42 | -0.11 | -0.11 |
| 458.93 | 1.01 | 1.01 |
| 503.38 | 1.12 | 1.12 |