Basic Information
ID: ALA3418013
Type: Binding
Description: Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biotinylated 45-bp unmethylated or hemimethylated oligonucleotide substrates and [3H]-AdoMet by liquid scintillation counting method
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA3418013
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.53 | 5.65 | 5.65 |
| 461.53 | 5.65 | 5.65 |
| 521.43 | 2.03 | 2.03 |
| 378.79 | 3.91 | 3.91 |