Assay Report Card

Basic Information

ID: ALA3418014

Type: Binding

Description: Inhibition of His6-tagged human recombinant DNMT3b expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biotinylated 45-bp unmethylated or hemimethylated oligonucleotide substrates and [3H]-AdoMet by liquid scintillation counting method

Organism: Homo sapiens

Cell type: Sf9

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
302.281.721.72
461.535.655.65