Basic Information
ID: ALA3418015
Type: Binding
Description: Inhibition of His6-tagged human recombinant DNMT3A/DNMT3L expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biotinylated 45-bp unmethylated or hemimethylated oligonucleotide substrates and [3H]-AdoMet by liquid scintillation counting method
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA3418015
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 235.33 | 1.34 | 1.34 |
| 227.05 | 2.75 | 2.75 |
| 334.33 | 2.46 | 2.46 |
| 548.77 | 6.37 | 6.37 |