Basic Information
ID: ALA3418034
Type: Binding
Description: Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in DNA 3' end directed cleavage using HTS-2 RNA/DNA duplex substrate by fluorescence assay
Organism: Human immunodeficiency virus 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3418034
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 177.16 | 0.60 | 0.60 |
| 267.28 | 2.19 | 2.19 |
| 281.31 | 2.50 | 2.50 |
| 285.27 | 2.33 | 2.33 |
| 301.73 | 2.84 | 2.84 |
| 346.18 | 2.95 | 2.95 |
| 335.28 | 3.21 | 3.21 |
| 303.26 | 2.47 | 2.47 |
| 307.35 | 3.07 | 3.07 |
| 343.38 | 3.86 | 3.86 |
| 349.41 | 3.92 | 3.92 |
| 361.37 | 4.00 | 4.00 |
| 368.39 | 3.73 | 3.73 |
| 373.41 | 3.87 | 3.87 |
| 421.47 | 3.26 | 3.26 |
| 422.46 | 2.51 | 2.51 |
| 386.41 | 2.96 | 2.96 |
| 379.36 | 4.14 | 4.14 |
| 479.38 | 5.90 | 5.90 |
| 391.40 | 4.01 | 4.01 |
| 516.58 | 3.25 | 3.25 |