Basic Information
ID: ALA3418039
Type: Binding
Description: Inhibition of HIV1 reverse transcriptase Y181C mutant associated RNase H domain activity assessed as reduction in reduction in DNA 3' end directed cleavage using HTS-1 RNA/DNA duplex substrate by fluorescence assay
Organism: Human immunodeficiency virus 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3418039
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 301.73 | 2.84 | 2.84 |
| 343.38 | 3.86 | 3.86 |
| 361.37 | 4.00 | 4.00 |
| 368.39 | 3.73 | 3.73 |
| 373.41 | 3.87 | 3.87 |
| 421.47 | 3.26 | 3.26 |
| 422.46 | 2.51 | 2.51 |