Basic Information
ID: ALA3418717
Type: Binding
Description: Antagonist activity at recombinant human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced intracellular ethidium bromide uptake after 2 hrs by fluorescence assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3418717
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 721.86 | 5.13 | 5.13 |
| 608.72 | 4.50 | 4.50 |
| 598.73 | 4.77 | 4.77 |
| 612.71 | 4.41 | 4.41 |
| 536.61 | 2.87 | 2.87 |
| 550.64 | 3.11 | 3.11 |
| 564.66 | 3.50 | 3.50 |
| 550.64 | 3.26 | 3.26 |
| 564.66 | 3.50 | 3.50 |
| 590.70 | 4.04 | 4.04 |
| 642.78 | 4.67 | 4.67 |
| 735.86 | 6.57 | 6.57 |
| 725.87 | 6.84 | 6.84 |
| 735.86 | 6.57 | 6.57 |
| 538.59 | 4.21 | 4.21 |
| 594.69 | 4.11 | 4.11 |
| 538.59 | 4.21 | 4.21 |
| 584.70 | 4.38 | 4.38 |
| 594.69 | 4.11 | 4.11 |
| 580.66 | 3.86 | 3.86 |
| 570.67 | 4.13 | 4.13 |
| 584.65 | 3.77 | 3.77 |
| 598.68 | 4.02 | 4.02 |
| 628.79 | 5.15 | 5.15 |
| 656.80 | 5.06 | 5.06 |
| 721.67 | 5.19 | 5.19 |
| 670.83 | 5.45 | 5.45 |
| 628.75 | 4.28 | 4.28 |
| 616.74 | 4.28 | 4.28 |
| 644.71 | 3.79 | 3.79 |
| 619.10 | 4.42 | 4.42 |
| 619.10 | 4.42 | 4.42 |
| 619.10 | 4.42 | 4.42 |
| 602.64 | 3.91 | 3.91 |
| 620.63 | 4.05 | 4.05 |
| 653.54 | 5.08 | 5.08 |
| 687.10 | 5.44 | 5.44 |
| 637.09 | 4.56 | 4.56 |
| 701.12 | 5.78 | 5.78 |
| 715.15 | 6.17 | 6.17 |
| 729.18 | 6.56 | 6.56 |
| 729.18 | 6.56 | 6.56 |