Basic Information
ID: ALA3418950
Type: Binding
Description: Inhibition of Syk in anti-CD32 stimulated CD14+ human monocytes assessed as phospho-SLP76 level preincubated for 30 mins followed by anti-CD32 stimulation measured after 5 mins by flow cytometric analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosine-protein kinase SYK(ALA2599)
Document: ALA3414433
Inhibition of Syk in anti-CD32 stimulated CD14+ human monocytes assessed as phospho-SLP76 level preincubated for 30 mins followed by anti-CD32 stimulation measured after 5 mins by flow cytometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3418950
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.45 | 1.58 | 1.58 |
| 417.48 | 2.32 | 2.32 |
| 389.46 | 3.22 | 3.22 |
| 390.45 | 2.68 | 2.68 |
| 411.47 | 3.85 | 3.85 |
| 392.47 | 2.19 | 2.19 |
| 364.45 | 3.09 | 3.09 |
| 393.46 | 1.58 | 1.58 |
| 365.44 | 2.48 | 2.48 |
| 394.44 | 0.98 | 0.98 |
| 366.43 | 1.88 | 1.88 |
| 366.43 | 1.88 | 1.88 |
| 365.44 | 2.48 | 2.48 |