Basic Information
ID: ALA3419140
Type: Binding
Description: Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenzyme A production after 45 mins by CoA-based HTS counter screen assay
Organism: Saccharomyces cerevisiae
Activity Charts
Bioactivity
Activity Types for Assay ALA3419140
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 173.17 | 1.12 | 1.12 |
| 289.66 | 1.96 | 1.96 |
| 207.62 | 1.77 | 1.77 |
| 252.07 | 1.88 | 1.88 |
| 187.20 | 1.42 | 1.42 |
| 203.20 | 1.12 | 1.12 |
| 191.16 | 1.26 | 1.26 |
| 434.45 | 3.43 | 3.43 |
| 468.35 | 4.29 | 4.29 |
| 398.47 | 3.62 | 3.62 |
| 380.43 | 2.90 | 2.90 |
| 348.27 | 2.98 | 2.98 |
| 381.41 | 3.17 | 3.17 |
| 274.31 | 1.23 | 1.23 |
| 319.77 | 1.70 | 1.70 |
| 390.49 | 3.59 | 3.59 |
| 458.56 | 6.05 | 6.05 |
| 367.39 | 2.87 | 2.87 |
| 362.30 | 3.44 | 3.44 |
| 342.40 | 3.61 | 3.61 |
| 394.46 | 3.21 | 3.21 |
| 223.23 | 2.27 | 2.27 |
| 319.82 | 2.68 | 2.68 |
| 424.37 | 4.70 | 4.70 |
| 410.34 | 4.83 | 4.83 |
| 432.91 | 4.27 | 4.27 |
| 448.53 | 4.77 | 4.77 |
| 433.46 | 3.22 | 3.22 |
| 265.27 | 2.91 | 2.91 |
| 466.54 | 5.55 | 5.55 |
| 477.37 | 4.38 | 4.38 |
| 475.56 | 4.47 | 4.47 |
| 440.55 | 4.74 | 4.74 |
| 445.56 | 4.82 | 4.82 |
| 386.41 | 2.24 | 2.24 |
| 390.54 | 4.54 | 4.54 |
| 328.47 | 3.14 | 3.14 |
| 346.39 | 3.52 | 3.52 |
| 386.45 | 3.55 | 3.55 |
| 320.39 | 2.55 | 2.55 |
| 387.40 | 3.52 | 3.52 |
| 432.48 | 3.64 | 3.64 |
| 342.41 | 2.54 | 2.54 |
| 343.39 | 3.01 | 3.01 |
| 410.24 | 3.18 | 3.18 |
| 341.31 | 2.26 | 2.26 |
| 371.33 | 3.34 | 3.34 |
| 354.35 | 3.08 | 3.08 |
| 375.76 | 2.91 | 2.91 |
| 321.75 | 4.08 | 4.08 |
| 307.72 | 3.94 | 3.94 |
| 436.27 | 3.75 | 3.75 |
| 472.51 | 4.17 | 4.17 |
| 414.40 | 2.76 | 2.76 |
| 341.31 | 3.33 | 3.33 |
| 442.32 | 4.00 | 4.00 |
| 313.30 | 3.16 | 3.16 |
| 280.29 | 1.87 | 1.87 |
| 365.79 | 3.07 | 3.07 |
| 377.39 | 1.24 | 1.24 |
| 425.25 | 2.76 | 2.76 |
| 370.35 | 3.08 | 3.08 |
| 303.82 | 3.13 | 3.13 |
| 379.92 | 4.89 | 4.89 |
| 423.97 | 5.21 | 5.21 |
| 505.98 | 6.56 | 6.56 |
| 579.68 | 4.60 | 4.60 |
| 534.11 | 6.31 | 6.31 |
| 564.53 | 6.00 | 6.00 |
| 520.01 | 6.62 | 6.62 |
| 458.01 | 4.58 | 4.58 |
| 598.10 | 6.31 | 6.31 |
| 578.56 | 6.31 | 6.31 |
| 538.49 | 5.43 | 5.43 |
| 512.87 | 5.58 | 5.58 |
| 527.44 | 5.50 | 5.50 |
| 424.37 | 4.89 | 4.89 |
| 446.28 | 3.63 | 3.63 |
| 414.87 | 3.56 | 3.56 |
| 442.50 | 4.69 | 4.69 |
| 364.43 | 3.00 | 3.00 |
| 381.41 | 3.17 | 3.17 |
| 456.53 | 5.00 | 5.00 |
| 396.39 | 1.99 | 1.99 |
| 414.49 | 4.36 | 4.36 |
| 419.29 | 4.00 | 4.00 |
| 384.28 | 3.03 | 3.03 |
| 242.06 | 2.42 | 2.42 |
| 482.38 | 4.68 | 4.68 |
| 412.69 | 4.76 | 4.76 |
| 422.26 | 3.81 | 3.81 |
| 455.99 | 6.46 | 6.46 |
| 445.56 | 5.04 | 5.04 |
| 411.50 | 5.23 | 5.23 |
| 464.59 | 6.11 | 6.11 |
| 489.58 | 4.78 | 4.78 |
| 396.24 | 4.25 | 4.25 |
| 407.52 | 5.50 | 5.50 |
| 423.24 | 4.02 | 4.02 |
| 428.31 | 5.26 | 5.26 |
| 420.33 | 5.03 | 5.03 |
| 362.63 | 3.61 | 3.61 |
| 339.84 | 4.14 | 4.14 |
| 370.27 | 4.08 | 4.08 |