Basic Information
ID: ALA3419529
Type: Binding
Description: Displacement of fluorescently labeled 3'-chloro-N-(2-(3-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-5-yl)thioureido)ethyl)-4'-((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)biphenyl-4-carboxamide from Escherichia coli recombinant 6-His-tagged FimH CRD expressed in Escherichia coli HM125 after 24 hrs by fluorescence polarization assay
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA3419529
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 332.35 | 0.53 | 0.53 |
| 390.39 | 0.32 | 0.32 |
| 357.36 | 0.40 | 0.40 |
| 278.35 | -0.23 | -0.23 |
| 376.36 | 0.23 | 0.23 |
| 400.39 | -0.29 | -0.29 |
| 400.39 | -0.26 | -0.26 |
| 391.81 | 1.06 | 1.06 |
| 375.38 | -0.37 | -0.37 |
| 389.40 | -0.11 | -0.11 |
| 445.47 | 0.00 | 0.00 |
| 410.44 | -0.06 | -0.06 |
| 425.46 | -0.56 | -0.56 |
| 384.33 | 0.52 | 0.52 |