Metabolic stability in monkey hepatocytes assessed as formation of 2-(7-(3-((1R,2S)-2-aminocyclohexylamino)-6-carbamoyl-1,2,4-triazin-5-ylamino)-3-oxo...

Basic Information

ID: ALA3419938

Type: ADME

Description: Metabolic stability in monkey hepatocytes assessed as formation of 2-(7-(3-((1R,2S)-2-aminocyclohexylamino)-6-carbamoyl-1,2,4-triazin-5-ylamino)-3-oxo-3H-indol-2-ylamino)-3-mercaptopropanoic acid by measuring parent compound level at 10 uM after 6 hrs

Format: BAO_0000219

Organism: Macaca mulatta

Cell type: Hepatocyte

Target:  ADMET(ALA612558)

Document:  ALA3414433

Metabolic stability in monkey hepatocytes assessed as formation of 2-(7-(3-((1R,2S)-2-aminocyclohexylamino)-6-carbamoyl-1,2,4-triazin-5-ylamino)-3-oxo-3H-indol-2-ylamino)-3-mercaptopropanoic acid by measuring parent compound level at 10 uM after 6 hrs: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
366.431.881.88