Basic Information
ID: ALA3420629
Type: Binding
Description: Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed by stimulation with A23187 for 10 mins by RP-HPLC based cell based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3420629
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 294.39 | 4.31 | 4.31 |
| 252.31 | 3.14 | 3.14 |
| 322.45 | 5.09 | 5.09 |
| 350.50 | 5.87 | 5.87 |
| 308.42 | 4.40 | 4.40 |
| 350.50 | 5.57 | 5.57 |
| 308.42 | 4.10 | 4.10 |
| 336.47 | 5.18 | 5.18 |
| 322.44 | 4.49 | 4.49 |
| 224.26 | 2.36 | 2.36 |
| 196.20 | 1.58 | 1.58 |
| 280.36 | 3.92 | 3.92 |
| 308.42 | 4.70 | 4.70 |
| 336.47 | 5.48 | 5.48 |
| 364.53 | 6.26 | 6.26 |
| 276.33 | 3.48 | 3.48 |
| 344.45 | 5.20 | 5.20 |
| 210.23 | 1.67 | 1.67 |
| 238.28 | 2.45 | 2.45 |
| 266.34 | 3.23 | 3.23 |
| 294.39 | 4.01 | 4.01 |
| 322.45 | 4.79 | 4.79 |
| 364.53 | 5.96 | 5.96 |
| 378.55 | 6.35 | 6.35 |
| 290.36 | 3.56 | 3.56 |
| 358.48 | 5.29 | 5.29 |
| 224.26 | 1.76 | 1.76 |
| 252.31 | 2.54 | 2.54 |
| 280.36 | 3.32 | 3.32 |
| 336.47 | 4.88 | 4.88 |
| 350.50 | 5.27 | 5.27 |
| 364.53 | 5.66 | 5.66 |
| 378.55 | 6.05 | 6.05 |
| 392.58 | 6.44 | 6.44 |
| 304.39 | 3.65 | 3.65 |
| 372.51 | 5.38 | 5.38 |
| 224.26 | 1.76 | 1.76 |
| 252.31 | 2.54 | 2.54 |
| 280.36 | 3.32 | 3.32 |
| 308.42 | 4.10 | 4.10 |
| 322.44 | 4.49 | 4.49 |
| 336.47 | 4.88 | 4.88 |
| 350.50 | 5.27 | 5.27 |
| 364.53 | 5.66 | 5.66 |
| 378.55 | 6.05 | 6.05 |
| 392.58 | 6.44 | 6.44 |
| 304.39 | 3.65 | 3.65 |
| 372.51 | 5.38 | 5.38 |