Basic Information
ID: ALA3420841
Type: Binding
Description: Inhibition of FLAP in calcimycin-stimulated human whole blood assessed as inhibition of LTB4 synthesis preincubated for 15 mins followed by calcimycin stimulation measured after 30 mins
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA3420841
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.35 | 2.16 | 2.16 |
| 336.40 | 3.01 | 3.01 |
| 386.44 | 1.95 | 1.95 |
| 369.43 | 4.25 | 4.25 |
| 370.42 | 3.64 | 3.64 |
| 371.40 | 3.04 | 3.04 |
| 371.40 | 3.04 | 3.04 |
| 371.40 | 3.04 | 3.04 |
| 371.40 | 3.04 | 3.04 |
| 371.40 | 3.04 | 3.04 |
| 386.42 | 2.93 | 2.93 |
| 359.39 | 2.97 | 2.97 |
| 360.38 | 2.36 | 2.36 |
| 360.38 | 2.36 | 2.36 |
| 376.45 | 3.70 | 3.70 |
| 360.38 | 3.23 | 3.23 |
| 359.39 | 2.97 | 2.97 |
| 359.39 | 2.97 | 2.97 |
| 373.42 | 2.98 | 2.98 |
| 417.43 | 2.53 | 2.53 |
| 417.47 | 3.09 | 3.09 |
| 402.46 | 2.40 | 2.40 |
| 430.52 | 3.00 | 3.00 |
| 444.50 | 2.53 | 2.53 |
| 431.50 | 3.21 | 3.21 |
| 333.36 | 2.10 | 2.10 |
| 361.41 | 2.84 | 2.84 |
| 359.39 | 2.59 | 2.59 |
| 401.47 | 3.62 | 3.62 |
| 375.44 | 3.30 | 3.30 |
| 389.46 | 3.47 | 3.47 |
| 389.46 | 3.47 | 3.47 |
| 389.46 | 3.47 | 3.47 |
| 387.45 | 3.23 | 3.23 |
| 387.45 | 3.23 | 3.23 |
| 401.47 | 3.62 | 3.62 |
| 401.47 | 3.62 | 3.62 |
| 457.54 | 3.38 | 3.38 |
| 458.53 | 2.78 | 2.78 |
| 458.53 | 2.78 | 2.78 |
| 472.55 | 3.24 | 3.24 |
| 486.58 | 3.63 | 3.63 |
| 500.61 | 4.01 | 4.01 |
| 444.54 | 3.25 | 3.25 |
| 445.53 | 3.46 | 3.46 |