Basic Information
ID: ALA3420844
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by NADPH addition measured after 6 mins
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3420844
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.52 | 3.00 | 3.00 |
| 431.50 | 3.21 | 3.21 |
| 458.53 | 2.78 | 2.78 |
| 444.54 | 3.25 | 3.25 |
| 445.53 | 3.46 | 3.46 |