Basic Information
ID: ALA3420868
Type: Binding
Description: Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as remaining activity by measuring lipoxygenase products formation at 10 uM in presence of arachidonic acid pre-incubated for 15 mins followed by stimulation with A23187 for 10 mins by RP-HPLC based cell based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3420868
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 252.31 | 3.14 | 3.14 |
| 350.50 | 5.87 | 5.87 |
| 224.26 | 2.36 | 2.36 |
| 196.20 | 1.58 | 1.58 |
| 364.53 | 6.26 | 6.26 |
| 276.33 | 3.48 | 3.48 |
| 344.45 | 5.20 | 5.20 |
| 210.23 | 1.67 | 1.67 |
| 238.28 | 2.45 | 2.45 |
| 266.34 | 3.23 | 3.23 |
| 290.36 | 3.56 | 3.56 |
| 378.55 | 6.05 | 6.05 |