Basic Information
ID: ALA3420915
Type: Binding
Description: Inhibition of p-gp (unknown origin) in doxorubicin-resistant human K562/R7 cells assessed as increase in daunorubicin accumulation measured as fluorescence ratio at 10 uM incubated for 1 hr with 10 uM daunorubicin by flow cytometry relative to control
Organism: Homo sapiens
Cell type: K562/R7
Activity Charts
Bioactivity
Activity Types for Assay ALA3420915
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 314.47 | 4.72 | 4.72 |
| 1202.63 | ||
| 330.47 | 3.84 | 3.84 |
| 316.49 | 4.80 | 4.80 |
| 316.49 | 4.80 | 4.80 |
| 429.60 | 5.41 | 5.41 |
| 330.47 | 3.69 | 3.69 |
| 414.59 | 5.25 | 5.25 |
| 414.59 | 5.39 | 5.39 |
| 414.59 | 5.39 | 5.39 |
| 414.59 | 5.25 | 5.25 |
| 436.59 | 5.64 | 5.64 |
| 416.60 | 5.33 | 5.33 |
| 332.48 | 3.77 | 3.77 |
| 416.60 | 5.33 | 5.33 |
| 416.60 | 5.33 | 5.33 |
| 332.48 | 3.92 | 3.92 |
| 416.60 | 5.47 | 5.47 |
| 416.60 | 5.47 | 5.47 |
| 452.59 | 4.61 | 4.61 |
| 556.70 | 6.47 | 6.47 |
| 536.71 | 6.16 | 6.16 |
| 536.71 | 6.16 | 6.16 |
| 348.48 | 2.75 | 2.75 |
| 516.72 | 5.85 | 5.85 |
| 516.72 | 5.85 | 5.85 |
| 536.71 | 6.16 | 6.16 |
| 536.71 | 6.16 | 6.16 |
| 452.59 | 4.61 | 4.61 |
| 348.48 | 2.89 | 2.89 |
| 516.72 | 5.99 | 5.99 |
| 556.70 | 6.47 | 6.47 |
| 536.71 | 6.16 | 6.16 |
| 536.71 | 6.16 | 6.16 |
| 420.59 | 3.75 | 3.75 |
| 628.81 | 7.47 | 7.47 |
| 588.83 | 6.85 | 6.85 |
| 584.79 | 6.40 | 6.40 |
| 608.82 | 7.16 | 7.16 |
| 608.82 | 7.16 | 7.16 |
| 608.82 | 7.16 | 7.16 |
| 608.82 | 7.16 | 7.16 |
| 464.64 | 4.37 | 4.37 |
| 464.64 | 4.37 | 4.37 |
| 568.75 | 6.24 | 6.24 |
| 568.75 | 6.24 | 6.24 |
| 614.82 | 7.95 | 7.95 |
| 594.83 | 7.63 | 7.63 |
| 594.83 | 7.63 | 7.63 |
| 594.83 | 7.63 | 7.63 |
| 594.83 | 7.63 | 7.63 |