Basic Information
ID: ALA3420965
Type: Binding
Description: Inhibition of N-terminal His6-tagged human SETD8 (191 to 352) assessed as incorporation of [3H]-methyl group from [3H-Me]-SAM to biotinylated H4K20 peptide substrate preincubated for 10 mins followed by substrate addition by liquid scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3420965
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 321.76 | 0.83 | 0.83 |
| 241.25 | 2.05 | 2.05 |
| 284.34 | 3.30 | 3.30 |