Basic Information
ID: ALA3421140
Type: Binding
Description: Inhibition of recombinant His6-tagged Pseudomonas aeruginosa PqsD expressed in Escherichia coli BL21 (deltaDE3) using anthraniloyl-CoA/beta-ketodecanoic acid as substrate assessed as HHQ formation preincubated for 10 mins followed by substrate addition by HPLC/MS-MS analysis
Organism: Pseudomonas aeruginosa
Activity Charts
Bioactivity
Activity Types for Assay ALA3421140
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 153.14 | 1.09 | 1.09 |
| 229.24 | 2.68 | 2.68 |
| 350.35 | 2.33 | 2.33 |
| 440.48 | 3.94 | 3.94 |
| 386.32 | 2.38 | 2.38 |
| 442.45 | 3.77 | 3.77 |
| 456.48 | 4.08 | 4.08 |
| 460.90 | 4.72 | 4.72 |
| 454.50 | 4.33 | 4.33 |
| 392.43 | 3.35 | 3.35 |
| 380.38 | 1.69 | 1.69 |
| 407.40 | 1.57 | 1.57 |
| 479.51 | 4.42 | 4.42 |
| 422.42 | 2.56 | 2.56 |
| 426.45 | 3.64 | 3.64 |
| 410.45 | 3.93 | 3.93 |
| 454.50 | 4.25 | 4.25 |
| 468.53 | 3.34 | 3.34 |
| 396.47 | 4.24 | 4.24 |
| 486.55 | 5.60 | 5.60 |
| 516.58 | 5.09 | 5.09 |
| 486.55 | 5.60 | 5.60 |
| 516.58 | 5.09 | 5.09 |
| 637.67 | 6.59 | 6.59 |
| 541.65 | 4.25 | 4.25 |
| 2152.61 |