Basic Information
ID: ALA3421220
Type: Binding
Description: Competitive inhibition of human DOT1L (1 to 472) using oligo-nucleosome as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins in presence of SAM
Format: BAO_0000357
Organism: Homo sapiens
Target: Histone-lysine N-methyltransferase, H3 lysine-79 specific(ALA1795117)
Document: ALA3414551
Competitive inhibition of human DOT1L (1 to 472) using oligo-nucleosome as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins in presence of SAM: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3421220
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.45 | -0.98 | -0.98 |